Apart from the self-renewal capability, the use of stem cells may reduce the need for repetitive administrations. There are several reasons for the use of stem cells in gene therapy, first being that they can readily be removed from the body. Even though the cells are present in small numbers, they can be removed from the bone marrow of adults, or via circulating blood or the umbilical cord blood of neonatal children. Furthermore, stem cells can be easily detected and controlled in the lab before being injected back into the patients. Hematopoietic stem cells have the ability to produce numerous types of blood cells including natural killer cells, T and B lympohyctes, macrophages, monocytes, megakaryocytes, granulocytes, eosinophils and basophils.
Most Downloaded Mitochondrion Articles - Elsevier
Mitochondria Mitochondria are tiny organelles found in nearly all eukaryotic cells. They are rather large organelles ranging from 0. The mitochondria are the energy factories of the cell and are located in the cytoplasm. They are the sites of cellular respiration. The mitochondria are responsible for generating ATP from such organic fuels as simple sugars and fats in the process of cellular respiration. This doubled-membrane organelle has its own DNA and.
Studies on Isolated Mitochondria – Organization
Ethnopharmacological relevance: Shilajit has been used as a rejuvenator for ages in Indian ancient traditional medicine and has been validated for a number of pharmacological activities. The mitochondrial bioenergetics and the activity of hypothalamus-pituitary-adrenal HPA axis were evaluated for the plausible mechanism of action of shilajit. Materials and methods: CFS was induced by forcing the rats to swim for 15mins for 21 consecutive days. The behavioral consequence of CFS was measured in terms of immobility and the climbing period. Plasma corticosterone and adrenal gland weight were estimated as indices of HPA axis activity.
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