Therapeutic vaccination for the treatment of metastatic breast cancer. Metastatic breast cancer is a leading cause of cancer-related mortality worldwide. While existing interventions are effective at treating localized tumors, disseminated malignancies remain incurable. Briefly, this approach entails a vaccine prime consisting of tumor lysate antigens encapsulated within poly lactic-co-glycolic acid PLGA microparticles MPs.
Breast cancer metastatic dormancy and emergence, a role for adjuvant statin therapy
"Turning Up Antitumor Immunity Against Breast Cancer" by Johnie Hodge
The specific signs and symptoms a person may have with metastatic breast cancer can vary significantly from one person to another. Some people will have many symptoms, whereas others may have very few symptoms or none at all, with the cancer being found on imaging tests such as a CT scan or PET scan alone. The particular symptoms you experience as well as the severity will also depend on a multitude of factors, including where your cancer has spread, the extent of the cancer, and your general health prior to the development of metastatic breast cancer. As you read about the possible symptoms you may experience, keep in mind that the majority of people do not experience all of these concerns.
How Metastatic Breast Cancer Is Diagnosed
In metastasis, cancer cells break away from where they first formed primary cancer , travel through the blood or lymph system, and form new tumors metastatic tumors in other parts of the body. The metastatic tumor is the same type of cancer as the primary tumor. Cancer that spreads from where it started to a distant part of the body is called metastatic cancer. For many types of cancer, it is also called stage IV 4 cancer. The process by which cancer cells spread to other parts of the body is called metastasis.
Beckwitt, Colin Breast cancer metastatic dormancy and emergence, a role for adjuvant statin therapy. Doctoral Dissertation, University of Pittsburgh. Breast cancer is responsible for the most new cancer cases and is the second highest cause of cancer related deaths among women. Localized breast cancer is effectively treated surgically.