An evidence pyramid visually depicts the evidential strength of different research designs. The image below is one of several available renderings of an evidence pyramid. Studies with the highest internal validity, characterized by a high degree of quantitative analysis, review, analysis, and stringent scientific methodoloy, are at the top of the pyramid. Observational research and expert opinion reside at the bottom of the pyramid.
Evidence-Based Medicine: Levels of Evidence
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Professional Reference articles are designed for health professionals to use. You may find one of our health articles more useful. NICE has issued rapid update guidelines in relation to many of these. This guidance is changing frequently.
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Developing NICE guidelines: the manual
Narrative reviews, often just called Reviews, articles may be evidence -based, but they are not evidence. Rather than answering a specific clinical question, they provide an overview of the research landscape on a given topic. Quasi-experimental Study. Level III. Non-experimental study.
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