Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health NIH in found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection. The changes included a marked decline in antiviral responses that correlated with clearance of virus from white blood cells. The analysis also showed that the preponderance of host responses shifted rapidly from activation of genes involved in cell damage and inflammation toward those linked to promotion of cellular and organ repair. This pivot came before the first signs of clinical improvement in the patient, who was admitted to the NIH Clinical Center on day 7 of illness and remained for 26 days. The patient received intensive supportive care, including fluids and electrolytes, but did not receive any experimental Ebola drugs.
What is Ebola Virus: History, Cause, Symptoms, Prevention and Treatment
Ebola virus epidemic in Guinea - Wikipedia
This is measured in a few ways. One key measure is the R0, or basic reproduction number , which indicates how many new cases one infected person generates. This is not just a measure of the inherent infectiousness of a disease. It also depends on other factors, including the rate of contact within a population and the duration of the infectious period.
LONDON -- A young child who became the first cross-border case of Ebola in the world's second-largest outbreak has died, health officials said. The 5-year-old boy sought medical care at a hospital in western Uganda on Monday evening after he and five relatives crossed into the country from the neighboring Democratic Republic of the Congo, which is struggling to contain one of the deadliest Ebola outbreaks in history. The boy was transferred to an Ebola treatment unit, where he and his family were placed under isolation and tested for Ebola virus disease, according to separate statements from the Ugandan and Congolese health ministries.
To become a paid subscriber, begin the process by registering. Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources. The following video s are recommended for use in association with this case study. Viral Life Cycle This short animation illustrates how delivery of a single virus to a cell allows the virus to infect the cell, replicate, and give rise to many progeny viruses.